Do you read emails when traveling? Or, do you wait until you return home and deal with an overflowing inbox?
There are pros and cons for both ways. It’s really up to you and way you like to travel as well as keeping up with your messages. I prefer checking emails occasionally while on vacation so I don’t have a huge amount to clean up once I return. It’s easy for me to delete the ones I really don’t need to spend any time dealing with and leave the ones I want to look at in depth. Plus, I can deal with anything of importance right then.
If you turn on your “out of office” feature while gone…don’t forget to turn it back on once you get home.